Dear Editor
Drs Passi and Oliver state in their article that ‘in-vivo studies to quantify the reduction in serum progesterone concentration following sugammadex have not been performed…’. They are incorrect in this statement.
Devoy et al performed a prospective observational study comparing changes in serum oestrogen and progesterone in women undergoing surgery. 60 patients on hormonal contraception received sugammadex; 30 patients were not on hormonal contraception and did not receive sugammadex; 32 patients were not on hormonal contraception and did receive sugammadex. Blood samples pre, 15-minutes post, 240 min post sugammadex administration were taken to measure oestrogen and progesterone levels.