Metabolomics and sepsis - Anaesthesia 2024 podcast
In the third of a series of podcasts recorded at the RCoA's Anaesthesia 2024 conference in Glasgow Professor Malcolm Sim discusses his research into the science of metabolomics, and its role in the diagnosis and treatment of sepsis.
Metabolomics sits at the end of an 'omics' chain, after genomics, transcriptomics, and proteomics. It can help, as Malcolm puts it, 'pierce the cloud' of uncertainty around sepsis, leading to better diagnosis, treatment, and outcomes.
Malcolm talks about the future of this research area and the opportunity to tailor therapies to a person's genetic or metabolic profile. He talks about how he was drawn towards anaesthesia, and what his other love - flying - has in common with the speciality.
Further reading:
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Professor Malcolm Sim is a Consultant in Anaesthesia and Intensive Care at the Queen Elizabeth University Hospital in Glasgow. He leads the Critical Care Research at this hospital. He undertook his MD in the Development and Application of Novel Intelligent Scoring Systems. He runs a portfolio of Investigator Led Trials in the areas High Flow Nasal Oxygen, Novel Nebulisation in Critical Care, Metabolomics in Sepsis and Immunometabolic Dysfunction in Critical Care. In addition, his team recruit into a number of national and international collaborations. He is the Chief Investigator for a number of local or UK wide studies. He is the academic representative to the Royal College of Anaesthetists' Scottish Board.